Description

3-Amino-2-Hydroxy-5-Methylhexanoic Acid is a specialized non-proteinogenic amino acid derivative with a unique branched-chain structure. This compound is valued for its role as a key chiral building block and intermediate in advanced organic synthesis, particularly for pharmaceuticals and bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors developing novel therapeutic agents and complex organic compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, especially in the development of enzyme inhibitors and receptor modulators.
• Peptide Synthesis: Used as a non-standard amino acid residue to introduce structural diversity and specific functionality into synthetic peptides and peptidomimetics.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and metabolic pathway research due to its structural similarity to natural amino acids.
• Fine Chemical Production: Acts as a versatile building block for the manufacture of complex organic molecules, including specialty chemicals and agrochemicals.
• Nutritional Science Studies: Investigated for its potential metabolic properties and interactions in studies related to branched-chain amino acid analogs.

Basic Information

Product Name	3-Amino-2-Hydroxy-5-Methylhexanoic Acid
CAS No.	62023-30-7
Molecular Formula	C7H15NO3
Molecular Weight	161.20 g/mol
Synonyms	5-Methyl-3-amino-2-hydroxyhexanoic acid; 2-Hydroxy-3-amino-5-methylhexanoic acid; AHMHA; (2R,3S)-3-Amino-2-hydroxy-5-methylhexanoic acid (for specific stereoisomer); L-3-Amino-2-hydroxy-5-methylhexanoic acid; β-Hydroxy-norleucine derivative; 3-Amino-2-hydroxy-5-methyl-caproic acid
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Hydroxy-5-Methylhexanoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity and impurity profile analysis, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for specified isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.