Description

4-Pyrimidineacetonitrile, α-Formyl- (9Ci) is a versatile pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its unique bifunctional structure, featuring both a nitrile and a formyl group on the pyrimidine core, makes it an invaluable intermediate for constructing complex heterocyclic systems. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other small molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging the pyrimidine scaffold's bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the preparation of specialty polymers and functional organic materials.
• Chemical Synthesis: A versatile synthon for constructing fused pyrimidine rings, such as pteridines and purine analogs, through cyclocondensation reactions.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	4-Pyrimidineacetonitrile, α-Formyl- (9Ci)
CAS No.	61959-37-3
Molecular Formula	C7H5N3O
Molecular Weight	147.14 g/mol
Synonyms	2-Formyl-2-(pyrimidin-4-yl)acetonitrile; 4-Pyrimidineacetonitrile, α-formyl-; (Pyrimidin-4-yl)(oxo)acetonitrile; 2-Oxo-2-(4-pyrimidinyl)acetonitrile; 4-Pyrimidineglyoxylonitrile; α-Formyl-4-pyrimidineacetonitrile
EINECS	Contact for details

Quality Control

Our 4-Pyrimidineacetonitrile, α-Formyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Our quality system is designed to support cGMP and ISO standards for reliable, batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.