Description

(D-Trp8,D-Cys14)-Somatostatin-14 is a synthetic, biologically active peptide analog of the endogenous hormone somatostatin-14, featuring specific D-amino acid substitutions at positions 8 and 14. This engineered structure confers enhanced metabolic stability and receptor selectivity, making it a valuable research tool and a key intermediate in pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuroendocrinology, oncology, and metabolic disorder research, as well as in the development of novel diagnostic and therapeutic agents.

Application

• Biomedical Research: Used as a selective agonist in studies of somatostatin receptor (SSTR) subtypes, particularly SSTR2 and SSTR5, to investigate signaling pathways and physiological functions.
• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of more complex peptide-based drugs and targeted radiopharmaceuticals.
• In Vitro Diagnostics: Employed in the development and calibration of immunoassays and receptor-binding assays for hormone research.
• Metabolic Studies: Applied in preclinical research to study the inhibition of growth hormone, insulin, and glucagon secretion.
• Oncology Research: Investigated for its potential role in targeting somatostatin receptor-expressing tumors, such as neuroendocrine tumors.
• Reference Standard: Used as a high-purity analytical standard for quality control in peptide manufacturing and research.

Basic Information

Product Name	(D-Trp8,D-Cys14)-Somatostatin-14
CAS No.	61950-59-2
Molecular Formula	C76H104N18O19S2
Molecular Weight	1637.9 g/mol
Synonyms	D-Trp8,D-Cys14-Somatostatin-14; BIM-23014; DC-14-SRIF; Somatostatin (8-D-tryptophan, 14-D-cysteine); Cyclo(Ala-Gly-Cys-Lys-Asn-Phe-Phe-D-Trp-Lys-Thr-Phe-Thr-Ser-D-Cys); SRIF-14 analog; Somatostatin-14 analog
EINECS	Contact for details

Quality Control

Our (D-Trp8,D-Cys14)-Somatostatin-14 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide Certificates of Analysis (COA) with detailed results for all critical parameters, ensuring traceability and compliance with research-grade standards. Specifications can be aligned with customer-specific requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and storage under inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.