Description

2-Iodo-7,8,9,10-Tetrahydroazepino[2,1-B]Quinazolin-12(6H)-One is a sophisticated heterocyclic organic compound featuring a fused quinazolinone and azepine ring system, functionalized with an iodine atom. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a key building block in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel drug candidates targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs) and potential drug molecules.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe: Used in the development of molecular probes to study biological pathways and protein functions, leveraging the reactivity of the iodine moiety.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) to construct more complex polycyclic structures.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for exploratory synthetic chemistry and novel heterocycle development.

Basic Information

Product Name	2-Iodo-7,8,9,10-Tetrahydroazepino[2,1-B]Quinazolin-12(6H)-One
CAS No.	61938-70-3
Molecular Formula	C13H12IN3O
Molecular Weight	353.16 g/mol
Synonyms	2-Iodo-6,7,8,9-tetrahydroazepino[2,1-b]quinazolin-12(5H)-one; 2-Iodo-5,6,7,8-tetrahydroazepino[2,1-b]quinazolin-12-one; Azepino[2,1-b]quinazolin-12(6H)-one, 2-iodo-7,8,9,10-tetrahydro-; 61938-70-3; 2-Iodo-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one
EINECS	Contact for details

Quality Control

Our 2-Iodo-7,8,9,10-Tetrahydroazepino[2,1-B]Quinazolin-12(6H)-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry for identity confirmation. Certificates of Analysis (COA) are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.