Description

L-β-Homoglutamic Acid Hydrochloride is a high-purity, non-proteinogenic amino acid derivative used as a critical building block in advanced chemical synthesis. This compound is essential for researchers and manufacturers requiring precise chiral control and high chemical purity for demanding applications. It serves as a key intermediate in pharmaceutical research, peptide chemistry, and the development of specialized biochemical tools.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in neurological and metabolic disorder research.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to introduce the β-homoglutamic acid moiety into peptide chains.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and as a standard in analytical method development for amino acid analysis.
• Ligand and Chelator Development: Acts as a precursor for synthesizing specialized chelating agents and ligands for metal catalysis or diagnostic imaging agents.
• Prodrug Design: Utilized in the design and synthesis of prodrugs where its carboxylic acid groups can be functionalized for targeted drug delivery.

Basic Information

Product Name	L-β-Homoglutamic Acid Hydrochloride
CAS No.	61884-74-0
Molecular Formula	C6H11NO4 • HCl
Molecular Weight	197.62 g/mol (Free base: 161.16)
Synonyms	(S)-2-Aminopimelic acid hydrochloride; L-2-Aminoheptanedioic acid hydrochloride; L-β-Homoglutamic acid HCl; H-βhGlu-OH • HCl; (2S)-2-Aminopimelic acid hydrochloride; L-α-Aminopimelic acid hydrochloride; β-Homo-L-glutamic acid hydrochloride
EINECS	Contact for details

Quality Control

Our L-β-Homoglutamic Acid Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for research and cGMP-grade pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.