Description

Z-Gly-Pro-Phe-Pro-Leu-Oh is a synthetic hexapeptide derivative, specifically a protected peptide sequence. This compound serves as a crucial intermediate in peptide synthesis and research, offering a defined structure for studying enzymatic cleavage, receptor binding, or as a building block for larger, more complex peptides. It is primarily utilized by pharmaceutical researchers, biotech companies, and academic institutions engaged in drug discovery, proteomics, and biochemical assay development.

Application

• Pharmaceutical Research Intermediate: Used as a key building block in the solid-phase or solution-phase synthesis of novel therapeutic peptides.
• Protease/Enzyme Substrate: Serves as a specific substrate for studying the activity and inhibition of proteolytic enzymes like prolyl oligopeptidase.
• Biochemical Tool Compound: Employed in biochemical assays to investigate peptide-protein interactions, signal transduction pathways, and cell permeability studies.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in peptide analysis using HPLC or LC-MS.
• Peptide Library Construction: Utilized in the generation of focused peptide libraries for screening in drug discovery programs.

Basic Information

Product Name	Z-Gly-Pro-Phe-Pro-Leu-Oh
CAS No.	61867-13-8
Molecular Formula	C41H51N7O9
Molecular Weight	785.90 g/mol
Synonyms	Z-Gly-Pro-Phe-Pro-Leu-OH; Z-Gly-Pro-Phe-Pro-Leu; Benzyloxycarbonyl-Glycyl-Prolyl-Phenylalanyl-Prolyl-Leucine; CBZ-Gly-Pro-Phe-Pro-Leu-OH; N-Carbobenzoxy-glycyl-prolyl-phenylalanyl-prolyl-leucine; Hexapeptide Z-Gly-Pro-Phe-Pro-Leu; Z-GPFPLeu-OH; (S)-5-((S)-2-((S)-2-((S)-2-((S)-2-((Benzyloxy)carbonylamino)acetamido)pyrrolidine-1-carbonyl)-3-phenylpropanamido)pyrrolidine-1-carbonyl)-2-amino-4-methylpentanoic acid
EINECS	Contact for details

Quality Control

Our Z-Gly-Pro-Phe-Pro-Leu-Oh is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and MS for identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all specified parameters to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider storing desiccated under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥95.0%
Single Impurity (HPLC)	≤1.0%
Water Content (KF)	≤5.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.