Description

Adenine, n-Benzyl-9-(Tetrahydro-2H-Pyran-2-Yl)- (8Ci) is a protected adenine derivative, a key building block in nucleoside chemistry and pharmaceutical synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates for the development of novel therapeutics and biochemical tools. It is primarily utilized by the pharmaceutical, biotechnology, and fine chemical industries for applications in antiviral and anticancer drug discovery, as well as in oligonucleotide synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of nucleoside analogs and modified oligonucleotides for antiviral and anticancer research.
• Biochemical Research: Used as a protected monomer in solid-phase synthesis for creating custom DNA/RNA sequences and probes.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex molecules requiring selective protection of the adenine moiety.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring nucleotide chemistry and enzyme mechanisms.

Basic Information

Product Name	Adenine, n-Benzyl-9-(Tetrahydro-2H-Pyran-2-Yl)- (8Ci)
CAS No.	61764-68-9
Molecular Formula	C₁₇H₂₁N₅O
Molecular Weight	311.38 g/mol
Synonyms	9-[(Tetrahydro-2H-pyran-2-yl)oxy]-N-benzyl-9H-purin-6-amine; N-Benzyl-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine; 6-(Benzylamino)-9-(tetrahydro-2-pyranyl)-9H-purine; 6-Benzylamino-9-tetrahydropyran-2-yl-purine; N6-Benzyl-9-(tetrahydro-2H-pyran-2-yl)adenine; THP-Protected N6-Benzyladenine; Adenine, N-benzyl-9-(tetrahydro-2H-pyran-2-yl)-
EINECS	Contact for details

Quality Control

Our Adenine, n-Benzyl-9-(Tetrahydro-2H-Pyran-2-Yl)- (8Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for research and synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.