Description

4-Fluoro-3-(Trifluoromethyl)Phenol is a versatile fluorinated phenolic compound, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and a trifluoromethyl group on the aromatic ring, imparts valuable properties such as enhanced lipophilicity, metabolic stability, and electronic effects. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with improved efficacy and performance.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens in the production of high-performance liquid crystal displays (LCDs).
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers, including polyarylates and epoxy resins, to enhance thermal and chemical resistance.
• Organic Electronics: Employed in the research and development of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A valuable reagent for exploring new reaction pathways and creating complex fluorinated molecules in academic and industrial R&D labs.

Basic Information

Product Name	4-Fluoro-3-(Trifluoromethyl)Phenol
CAS No.	61721-07-1
Molecular Formula	C7H4F4O
Molecular Weight	180.10 g/mol
Synonyms	4-Fluoro-α,α,α-trifluoro-m-cresol; 3-(Trifluoromethyl)-4-fluorophenol; 4-Fluoro-3-trifluoromethylphenol; 4-Fluoro-α,α,α-trifluoro-3-methylphenol; 1-Hydroxy-4-fluoro-3-(trifluoromethyl)benzene; 4-Fluoro-3-(trifluoromethyl)benzenol; 2-Fluoro-5-hydroxybenzotrifluoride; F-TFMP
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(Trifluoromethyl)Phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.