Description

3-[(Phosphonoacetyl)Amino]-L-Alanine is a specialized amino acid derivative that incorporates a phosphonoacetyl group, making it a valuable building block in advanced biochemical research and synthesis. This compound is particularly significant for its role as a key intermediate in the development of enzyme inhibitors and other bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, proteomics, and the development of novel therapeutic agents.

Application

• Medicinal Chemistry Intermediate: A crucial precursor for synthesizing phosphonate-based enzyme inhibitors targeting various metabolic pathways.
• Biochemical Research: Used in studies of amino acid metabolism and the design of substrate analogs for enzymatic assays.
• Proteomics & Peptide Synthesis: Serves as a modified amino acid residue for incorporating phosphonate motifs into synthetic peptides to study protein-protein interactions.
• Agrochemical Research: Investigated as a potential intermediate for developing novel plant growth regulators or herbicides with specific mode-of-action.
• Academic & Institutional R&D: Employed in university and government laboratories for fundamental research in bioorganic and pharmaceutical chemistry.

Basic Information

Product Name	3-[(Phosphonoacetyl)Amino]-L-Alanine
CAS No.	61596-48-3
Molecular Formula	C5H11N2O6P
Molecular Weight	226.13 g/mol
Synonyms	N-(Phosphonoacetyl)-L-alanine; L-Alanine, N-[(phosphonoacetyl)amino]-; Phosphonoacetylamino-L-alanine; PALA analog; N-Phosphonoacetylaminoalanine; (2S)-2-[[(2-phosphonoacetyl)amino]methyl]propanoic acid; N-Phosphonoacetyl-L-2,3-diaminopropionic acid derivative
EINECS	Contact for details

Quality Control

Our 3-[(Phosphonoacetyl)Amino]-L-Alanine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.