Description

5-Methyl-4-Phenylpyrimidin-2-Amine is a high-purity pyrimidine derivative, a versatile heterocyclic building block essential for advanced organic synthesis. Its core value lies in its role as a key intermediate for the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating new molecular entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport or host materials in electronic displays.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create molecular probes for studying biological pathways and enzyme functions.
• Academic & Contract Research: A valuable reagent for method development and exploratory chemistry in R&D laboratories.

Basic Information

Product Name	5-Methyl-4-Phenylpyrimidin-2-Amine
CAS No.	61541-77-3
Molecular Formula	C11H11N3
Molecular Weight	185.23 g/mol
Synonyms	2-Amino-5-methyl-4-phenylpyrimidine; 4-Phenyl-5-methylpyrimidin-2-amine; 5-Methyl-4-phenyl-2-pyrimidinamine; 2-Pyrimidinamine, 5-methyl-4-phenyl-; 4-Phenyl-5-methyl-2-pyrimidinamine
EINECS	Contact for details

Quality Control

Our 5-Methyl-4-Phenylpyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.