Description

Fibrinopeptide A, Human (Tfa) is a specific, trifluoroacetylated (Tfa) derivative of the human fibrinopeptide A peptide. This modified peptide is a critical biochemical tool for research into the mechanisms of blood coagulation and fibrinolysis. It is primarily utilized by researchers and developers in the fields of hemostasis, thrombosis research, and diagnostic assay development.

Application

• Biochemical Research: Used as a substrate or standard in enzymatic studies of thrombin activity and fibrinogen conversion.
• Diagnostic Development: Serves as a key component in the calibration and validation of immunoassays (e.g., ELISA) designed to measure fibrinopeptide A levels, which are biomarkers for thrombotic events.
• Pharmaceutical R&D: Employed in screening and characterizing potential anticoagulant or antithrombotic drug candidates that target the thrombin-fibrinogen interaction.
• Proteomics & Peptide Chemistry: Acts as a model peptide in studies involving peptide modification, stability, and analysis due to its defined Tfa-protected structure.
• Quality Control: Used as a reference standard by manufacturers of fibrinogen products or related diagnostic kits to ensure batch consistency and activity.

Basic Information

Product Name	Fibrinopeptide A, Human (Tfa)
CAS No.	61533-47-9
Molecular Formula	C92H123N25O33S2
Molecular Weight	~2170.2 g/mol
Synonyms	Human Fibrinopeptide A TFA; FPA (Tfa); Fibrinopeptide A (TFA salt); FpA, Human (Tfa); TFA-Fibrinopeptide A; N-α-Trifluoroacetyl Fibrinopeptide A; FPA (1-16), Human, TFA; ADSGEGDFLAEGGGVR (Tfa)
EINECS	Contact for details

Quality Control

Our Fibrinopeptide A, Human (Tfa) is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research and diagnostic applications. Each lot is characterized by advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and peptide content is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.