Description

Bathorhodopsin is a key intermediate photoproduct in the visual cycle, formed upon light absorption by the visual pigment rhodopsin. This compound is essential for studying the molecular mechanisms of vision, phototransduction, and the conformational changes in G-protein-coupled receptors. It is a critical biochemical reagent for researchers and developers in pharmaceutical discovery, biochemistry, and advanced life science research, particularly for investigating retinal diseases and designing novel optogenetic tools.

Application

• Biochemical Research: Fundamental studies on the visual photocycle, protein conformational dynamics, and signal transduction mechanisms.
• Pharmaceutical Development: Serving as a reference standard and tool compound for drug discovery programs targeting retinal disorders and ophthalmic diseases.
• Optogenetics: Research into light-sensitive proteins and the engineering of novel photoreceptors for neuromodulation and cellular control.
• Spectroscopic Analysis: As a standard for UV-Vis, FTIR, and Raman spectroscopy to understand chromophore-protein interactions.
• Enzyme & Receptor Studies: Investigating the activation and deactivation pathways of rhodopsin and related GPCRs.
• Academic & Industrial R&D: A vital reagent for universities, government labs, and biotech companies focused on photobiology and sensory systems.

Basic Information

Product Name	Bathorhodopsin
CAS No.	61489-81-4
Molecular Formula	C47H74N4O15S
Molecular Weight	967.17 g/mol
Synonyms	Bathorhodopsin; Pre-lumirhodopsin; Rhodopsin Batho-intermediate; 11-cis-Retinal, N-retinylideneopsin (photoisomerized); Visual Pigment Intermediate; Opsin, N-retinylidene- (photoisomerized)
EINECS	Contact for details

Quality Control

Our Bathorhodopsin is produced and handled under strict quality protocols to ensure high purity and batch-to-batch consistency for research applications. Each lot is characterized using advanced analytical techniques including HPLC, UV-Vis spectroscopy, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identification, and spectroscopic properties is provided with every shipment to support your regulatory and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	Orange to red solid or film
Identification (UV-Vis)	Characteristic absorption spectrum (λmax ~ 543 nm)
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95% (Area Percent)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in specific detergent buffers (e.g., n-Dodecyl β-D-maltoside)
Specific Absorptivity	Provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.