Description

L-Homocysteine, S-(2-Hydroxyethyl)- is a modified amino acid derivative of homocysteine, featuring a 2-hydroxyethyl thioether side chain. This structural modification makes it a valuable biochemical tool and a key intermediate in the synthesis of more complex sulfur-containing compounds and potential pharmaceutical agents. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and fine chemical synthesis sectors.

Application

• Biochemical Research: Used as a precursor or standard in studies related to homocysteine metabolism, oxidative stress, and cardiovascular disease models.
• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting enzymes in the transsulfuration pathway.
• Reference Standard: Employed as a high-purity analytical standard in HPLC, LC-MS, or NMR for method development and quality control in clinical and research laboratories.
• Peptide Synthesis: Acts as a modified cysteine analog for introducing specific thioether linkages or functional groups into synthetic peptides and proteins.
• Nutritional Science Studies: Utilized in in-vitro experiments to investigate the biological effects of homocysteine derivatives and related metabolites.
• Enzyme Substrate/Analog: Potential use as a substrate or inhibitor for enzymes like cystathionine β-synthase (CBS) in mechanistic and kinetic studies.

Basic Information

Product Name	L-Homocysteine, S-(2-Hydroxyethyl)-
CAS No.	61473-66-3
Molecular Formula	C7H15NO3S
Molecular Weight	193.26 g/mol
Synonyms	S-(2-Hydroxyethyl)-L-homocysteine; (2S)-2-Amino-4-[(2-hydroxyethyl)sulfanyl]butanoic acid; L-2-Amino-4-((2-hydroxyethyl)thio)butyric acid; 2-Amino-4-(2-hydroxyethylthio)butyric acid; Hcy-S-EtOH; Homocysteine S-(2-hydroxyethyl) derivative; NSC 334913
EINECS	Contact for details

Quality Control

Our L-Homocysteine, S-(2-Hydroxyethyl)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm the L-configuration, and spectroscopic identification (NMR, IR). Certificates of Analysis (COA) with detailed batch-specific results are available upon request to ensure traceability and meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]²⁰D: Specific range provided per COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.