Description

6-Methyl-2-Phenyl-4,5-Pyrimidinedicarboxylic Acid Dimethyl Ester is a high-purity, functionalized pyrimidine derivative serving as a critical advanced intermediate in organic synthesis. This compound matters for its role as a versatile building block in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to construct novel heterocyclic scaffolds with precision.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other biological pathways where the pyrimidine core is essential.
• Agrochemical Research: Used in the development of new active ingredients for herbicides, fungicides, or plant growth regulators that incorporate a substituted pyrimidine structure.
• Material Science: Serves as a monomer or functional component in the research of specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Synthesis Building Block: Employed in multi-step organic synthesis for the construction of complex polycyclic systems or as a substrate for further functionalization reactions like hydrolysis, reduction, or cross-coupling.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploration of new chemical reactions involving dicarboxylic ester functionalities on a heterocyclic ring.

Basic Information

Product Name	6-Methyl-2-Phenyl-4,5-Pyrimidinedicarboxylic Acid Dimethyl Ester
CAS No.	61416-99-7
Molecular Formula	C15H14N2O4
Molecular Weight	286.28 g/mol
Synonyms	Dimethyl 6-Methyl-2-phenylpyrimidine-4,5-dicarboxylate; 4,5-Pyrimidinedicarboxylic acid, 6-methyl-2-phenyl-, dimethyl ester; 2-Phenyl-6-methylpyrimidine-4,5-dicarboxylic acid dimethyl ester; 6-Methyl-2-phenylpyrimidine-4,5-dicarboxylic acid dimethyl ester; NSC 339586
EINECS	Contact for details

Quality Control

Our 6-Methyl-2-Phenyl-4,5-Pyrimidinedicarboxylic Acid Dimethyl Ester is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.