Description

6-Methyl-2-Phenyl-4,5-Pyrimidinedicarboxylic Acid is a high-purity, heterocyclic dicarboxylic acid derivative that serves as a critical advanced intermediate in organic synthesis. This compound matters for its role as a versatile building block in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and other small molecule therapeutic programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where the pyrimidine core provides specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and other functional organic materials due to its rigid, conjugated structure.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including novel cyclization and functionalization reactions.
• Fine Chemical Production: Incorporated into the manufacture of dyes, pigments, and other specialty chemicals requiring a defined heterocyclic architecture.

Basic Information

Product Name	6-Methyl-2-Phenyl-4,5-Pyrimidinedicarboxylic Acid
CAS No.	61416-98-6
Molecular Formula	C₁₄H₁₀N₂O₄
Molecular Weight	270.24 g/mol
Synonyms	4,5-Pyrimidinedicarboxylic acid, 6-methyl-2-phenyl-; 2-Phenyl-6-methylpyrimidine-4,5-dicarboxylic acid; 6-Methyl-2-phenylpyrimidine-4,5-dicarboxylic acid; NSC 403796; 4,5-Dicarboxy-6-methyl-2-phenylpyrimidine; 6-Methyl-2-phenyl-1H-pyrimidine-4,5-dicarboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Methyl-2-Phenyl-4,5-Pyrimidinedicarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.