Description

Propan-2-Yl (2S)-2-Amino-3-Methylbutanoate is a high-purity chiral ester derivative of L-Valine. This compound is valued for its role as a key protected intermediate in the synthesis of complex peptides and active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutics and advanced organic molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of peptide-based drugs and proprietary APIs.
• Peptide Chemistry: Used for the introduction and protection of the L-Valine moiety during solid-phase and solution-phase peptide synthesis.
• Proteomics Research: Serves as a reagent in biochemical research for studying protein structure and function.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective chemical reactions to create enantiomerically pure compounds.
• Fine Chemical Production: A key starting material for manufacturing specialized agrochemicals, flavors, and fragrances.

Basic Information

Product Name	Propan-2-Yl (2S)-2-Amino-3-Methylbutanoate
CAS No.	61393-65-5
Molecular Formula	C8H17NO2
Molecular Weight	159.23 g/mol
Synonyms	L-Valine Isopropyl Ester; (S)-Isopropyl 2-Amino-3-methylbutanoate; Isopropyl L-Valinate; (2S)-2-Amino-3-methylbutanoic Acid 1-Methylethyl Ester; Valine Isopropyl Ester; L-Valine 1-Methylethyl Ester; (S)-Valine Isopropyl Ester; 2-Amino-3-methyl-Butanoic Acid Isopropyl Ester
EINECS	Contact for details

Quality Control

Our Propan-2-Yl (2S)-2-Amino-3-Methylbutanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade standards suitable for pharmaceutical research and GMP applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.