Description

(Des-Tyr1)-Met-Enkephalin CAS NO 61370-88-5 is a synthetic peptide analog of the endogenous opioid peptide Met-enkephalin, specifically lacking the N-terminal tyrosine residue. This modification makes it a valuable research tool for studying opioid receptor pharmacology and signal transduction pathways without the full agonist activity. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in neuroscience, pain management, and peptide chemistry.

Application

• Neuroscience Research: Used as a reference compound and antagonist in studies of delta (δ) and mu (μ) opioid receptor function and distribution.
• Pharmacological Studies: Serves as a key intermediate or tool for investigating the structure-activity relationships (SAR) of enkephalin-derived peptides.
• Biochemical Assay Development: Employed in the development and validation of competitive binding assays (e.g., ELISA, RIA) and receptor activation studies.
• Pain Research: Acts as a control or modulating agent in experimental models to understand endogenous pain modulation mechanisms.
• Peptide Synthesis & Medicinal Chemistry: Used as a building block or precursor for the synthesis of more complex, modified opioid peptide analogs.

Basic Information

Product Name	(Des-Tyr1)-Met-Enkephalin
CAS No.	61370-88-5
Molecular Formula	C21H33N5O5S
Molecular Weight	467.58 g/mol
Synonyms	Met-Enkephalin (Des-Tyr1); H-Gly-Gly-Phe-Met-OH; Des-Tyrosine-Methionine Enkephalin; [Des-Tyr1]-Met-Enkephalin; Opioid Growth Factor (OGF) analog; (Des-Tyr)-Methionine Enkephalin; Glycyl-glycyl-L-phenylalanyl-L-methionine
EINECS	Contact for details

Quality Control

Our (Des-Tyr1)-Met-Enkephalin is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Amino Acid Composition	Conforms
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.