Description

N1,N12-Diacetylspermine CAS NO 61345-83-3 is a chemically modified derivative of the natural polyamine spermine, characterized by acetylation at both terminal primary amine groups. This modification alters its biochemical properties, making it a valuable reference standard and research tool in polyamine metabolism studies. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and diagnostic sectors for analytical and investigative purposes.

Application

• Biochemical Research: Used as a critical reference standard in the study of polyamine biosynthesis, catabolism, and their roles in cellular processes.
• Pharmaceutical Development: Serves as an intermediate or analytical standard in the research of therapeutic agents targeting polyamine pathways, which are relevant in oncology and neurology.
• Diagnostic Assays: Employed as a calibrator or control in the development of liquid chromatography-mass spectrometry (LC-MS) or immunoassay methods for polyamine quantification.
• Metabolomics Studies: Acts as a defined metabolite for profiling and validating analytical platforms studying metabolic disorders or disease biomarkers.
• Enzyme Activity Studies: Utilized as a substrate or inhibitor in assays for enzymes like spermidine/spermine N1-acetyltransferase (SSAT).

Basic Information

Product Name	N1,N12-Diacetylspermine
CAS No.	61345-83-3
Molecular Formula	C18H40N4O2
Molecular Weight	344.54 g/mol
Synonyms	N1,N12-Diacetylspermine; N1,N12-Diacetylspermine; Diacetylspermine; 1,12-Diacetylspermine; N1-Acetyl-N12-acetylspermine; Spermine Diacetate; Bis(acetylspermine); N1-Acetylspermine-12-acetamide
EINECS	Contact for details

Quality Control

Our N1,N12-Diacetylspermine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the product at -20°C under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.