Description

D-Alanine Methylamide Hcl is a chiral amino acid derivative of significant interest in pharmaceutical and biochemical research. This high-purity building block is essential for the synthesis of peptides and peptidomimetics, where its D-configuration provides crucial resistance to enzymatic degradation. It serves as a key intermediate for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, enabling the development of novel therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of active pharmaceutical ingredients (APIs) and peptide-based drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate D-alanine residues, enhancing metabolic stability.
• Biochemical Research: Employed in enzymatic studies and as a substrate or inhibitor in research exploring amino acid metabolism and chiral recognition.
• Proteomics & Diagnostics: Utilized in the preparation of specialized reagents and standards for analytical methods and diagnostic assays.
• Fine Chemical Synthesis: Serves as a versatile precursor in the synthesis of complex organic molecules, flavors, and fragrances requiring specific stereochemistry.
• Material Science: A potential monomer or modifier in the development of bio-inspired polymers and smart materials.

Basic Information

Product Name	D-Alanine Methylamide Hcl
CAS No.	61302-99-6
Molecular Formula	C₄H₁₀N₂O•HCl
Molecular Weight	138.59 g/mol (Free base: 102.14 g/mol)
Synonyms	D-2-Aminopropionyl methylamide hydrochloride; (R)-2-Aminopropionyl methylamide hydrochloride; Methylamide, D-alanine, hydrochloride; D-Ala-NHMe•HCl; D-Alanine methylamide hydrochloride; (R)-Alanine methylamide hydrochloride; D-Alanine-N-methylamide hydrochloride; N-Methyl-D-alaninamide hydrochloride
EINECS	Contact for details

Quality Control

Our D-Alanine Methylamide Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (D-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.