Description

Carboranylalanine is a specialized boron-containing amino acid analog, representing a critical building block in advanced materials and pharmaceutical research. Its unique carborane cage structure imparts exceptional thermal stability and hydrophobic character, enabling the development of novel compounds with tailored properties. This high-value intermediate is essential for researchers and manufacturers in boron neutron capture therapy (BNCT), pharmaceutical development, and the synthesis of heat-resistant polymers and advanced materials.

Application

• Boron Neutron Capture Therapy (BNCT): As a key precursor for synthesizing tumor-targeting boron delivery agents.
• Pharmaceutical Research: Incorporation into peptide and protein analogs to study structure-activity relationships and enhance metabolic stability.
• Advanced Material Science: Monomer for creating high-performance, thermally stable polymers and resins.
• Chemical Biology: Probe molecule for studying biological interactions and developing novel bioconjugates.
• Radiopharmaceuticals: Intermediate in the development of diagnostic and therapeutic agents.
• Catalysis & Ligand Design: Building block for creating novel ligands and catalysts with unique electronic properties.

Basic Information

Product Name	Carboranylalanine
CAS No.	61216-60-2
Molecular Formula	C5H12B10NO2
Molecular Weight	210.27 g/mol (approx.)
Synonyms	1-Amino-3-(1,2-dicarba-closo-dodecaboran(12)-1-yl)-propanoic acid; 3-(1,2-Dicarbadodecaboran(12)-1-yl)-L-alanine; L-Carboranylalanine; o-Carboranylalanine; BNCT Amino Acid; Boronated Alanine; Closo-Carboranylalanine
EINECS	Contact for details

Quality Control

Every batch of Carboranylalanine is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by HPLC, NMR, and elemental analysis. Our quality systems are designed to support cGMP and GLP compliance for critical pharmaceutical and biomedical uses.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake. For long-term storage, consider using desiccant or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.