Description

β-Endorphin (Human, Synthetic) is a synthetic polypeptide identical to the endogenous human neuropeptide, a potent endogenous opioid. This high-purity synthetic standard is critical for neuroscience research, pharmaceutical development, and diagnostic applications, providing a reliable reference material free from biological variability. It is essential for researchers and manufacturers in neuropharmacology, pain management studies, and the development of novel therapeutic agents targeting the opioid receptor system.

Application

• Neuroscience Research: Used as a reference standard in studies investigating the endogenous opioid system, stress response, pain modulation, and reward pathways.
• Pharmaceutical R&D: Serves as a critical tool in the discovery and development of new analgesics, antidepressants, and addiction treatments targeting opioid receptors.
• Biochemical Assay Development: Employed as a calibrant and control in the development and validation of immunoassays (ELISA, RIA) and receptor binding assays.
• Cell Culture & In Vitro Studies: Applied in cell-based models to study cellular signaling, gene expression, and physiological effects mediated by opioid receptors.
• Diagnostic Manufacturing: Utilized in the production of diagnostic kits and reagents for measuring endorphin levels in clinical and research settings.
• Academic & Institutional Research: A fundamental reagent for universities and research institutes conducting fundamental biological and pharmacological research.

Basic Information

Product Name	β-Endorphin (Human, Synthetic)
CAS No.	61214-51-5
Molecular Formula	C158H251N39O46S
Molecular Weight	3464.0 g/mol (approximate)
Synonyms	β-Endorphin; β-Endorphin; Human β-Endorphin; β-Lipotropin (61-91); LPH-(61-91); Corticotropin-like intermediate lobe peptide; CLIP; Endorphin; Opioid peptide; [Met]enkephalin-Arg6,Phe7; Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu
EINECS	Contact for details

Quality Control

Our synthetic β-Endorphin is manufactured under controlled conditions to ensure the highest standards of purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment, mass spectrometry for identity confirmation, and amino acid analysis. A detailed Certificate of Analysis (COA) providing full specification data is supplied with every shipment, supporting your quality and regulatory requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Biological Activity	Assessed by receptor binding assay (Data available)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.