Description

7-Cyano-7-Deazaguanosine is a chemically modified nucleoside analog, serving as a key synthetic intermediate and research tool in medicinal chemistry. Its core value lies in its structural similarity to guanosine, making it a versatile building block for the development of novel antiviral and anticancer agents. This compound is primarily needed by research institutions and pharmaceutical companies engaged in nucleoside chemistry, antiviral drug discovery, and the synthesis of modified RNA/DNA probes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of advanced nucleoside-based therapeutics, including potential antiviral and anticancer drugs.
• Antiviral Research: Used in the development and study of novel compounds targeting viral polymerases and replication mechanisms.
• Medicinal Chemistry: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Biochemical Research: Employed as a modified nucleoside in studies of enzyme kinetics, nucleic acid interactions, and metabolic pathways.
• Probe Synthesis: Utilized for creating labeled or modified nucleotides for diagnostic assays and molecular biology techniques.
• Academic & Industrial R&D: A fundamental reagent for laboratories exploring novel nucleoside chemistry and its biological applications.

Basic Information

Product Name	7-Cyano-7-Deazaguanosine
CAS No.	61210-21-7
Molecular Formula	C₁₁H₁₁N₅O₅
Molecular Weight	293.24 g/mol
Synonyms	7-Cyano-7-deazaguanosine; 7-CN-7-Deazaguanosine; 4-Amino-5-cyano-7-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; 7-Cyano-7-carbaguanosine; Tubercidin 7-carbonitrile derivative; PreQ0 riboside; 7-Cyano-7-carba-guanosine
EINECS	Contact for details

Quality Control

Our 7-Cyano-7-Deazaguanosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.