Description

4-Chloro-2-Fluorobenzaldehyde is a versatile aromatic aldehyde building block characterized by its halogen-substituted benzene ring. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries that need it include pharmaceutical R&D for creating active pharmaceutical ingredients (APIs), agrochemical manufacturing for novel crop protection agents, and specialty chemical producers for advanced material synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially in molecules containing halogenated aromatic systems.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated and chlorinated organic compounds used in electronic displays.
• Organic Synthesis & Research: A valuable reagent for introducing the 4-chloro-2-fluorobenzyl moiety in complex organic molecules via reactions like condensation, reduction, or nucleophilic addition.
• Dye & Pigment Intermediate: Employed in the manufacture of specialized dyes and pigments where halogen atoms influence color fastness and spectral properties.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct biaryl systems.

Basic Information

Product Name	4-Chloro-2-Fluorobenzaldehyde
CAS No.	61072-56-8
Molecular Formula	C7H4ClFO
Molecular Weight	158.56 g/mol
Synonyms	2-Fluoro-4-chlorobenzaldehyde; 4-Chloro-2-fluorobenzenecarboxaldehyde; 4-Chloro-2-fluorobenzaldehyde; 2-Fluoro-4-chlorobenzaldehyde; 4-Chloro-2-fluoro-benzaldehyde; Benzenecarboxaldehyde, 4-chloro-2-fluoro-; 4-Chloro-o-fluorobenzaldehyde
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluorobenzaldehyde undergoes rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) are available upon request, detailing batch-specific results for all critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider packaging under an inert atmosphere such as nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.