Description

Z-Nle-Pna is a high-purity, protected amino acid derivative widely used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring precise molecular control and high coupling efficiency in complex peptide sequences. It is particularly valuable for the pharmaceutical and biotechnology industries in the development of novel therapeutic peptides and research biochemicals.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled elongation of peptide chains in both Fmoc and Boc strategies.
• Pharmaceutical Research: Used in the research and development of peptide-based drugs, including hormone analogs and enzyme inhibitors.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or carriers.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive compounds.
• Biochemical Tool Development: Integral for creating labeled peptides, substrates for protease assays, and other specialized research reagents.

Basic Information

Product Name	Z-Nle-Pna
CAS No.	61043-22-9
Molecular Formula	C20H22N2O5
Molecular Weight	370.40 g/mol
Synonyms	Nα-Carbobenzoxy-Norleucine p-Nitroanilide; Z-Norleucine p-Nitroanilide; Cbz-Nle-pNA; N-CBZ-L-Norleucine 4-nitroanilide; Benzyl N-[(2S)-1-[(4-nitrophenyl)amino]-1-oxohexan-2-yl]carbamate; Z-L-Nle-pNA; CBZ-L-Norleucine-p-Nitroanilide
EINECS	Contact for details

Quality Control

Our Z-Nle-Pna is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as HPLC purity, chiral purity, and moisture content are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.