Description

2-Chloro-3-Oxo-Butyronitrile is a versatile chlorinated keto-nitrile building block, essential for advanced organic synthesis. Its reactive carbonyl and nitrile groups adjacent to a chlorine atom make it a critical intermediate for constructing complex heterocyclic and pharmaceutical scaffolds. This high-purity compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various heterocyclic compounds, including pyrazoles and pyrimidines, which are core structures in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, leveraging its reactivity to introduce chlorinated keto-nitrile motifs into target molecules.
• Organic Synthesis Building Block: Employed in nucleophilic substitution and condensation reactions to create complex molecules for material science and chemical research.
• Dye and Pigment Intermediate: Serves as a starting material for synthesizing specialized colorants and functional dyes.
• Polymer Modification: Can be used to introduce reactive sites into polymer chains for cross-linking or to impart specific chemical functionalities.

Basic Information

Product Name	2-Chloro-3-Oxo-Butyronitrile
CAS No.	60930-76-9
Molecular Formula	C₄H₄ClNO
Molecular Weight	117.53 g/mol
Synonyms	2-Chloroacetoacetonitrile; 3-Oxobutanenitrile, 2-chloro-; Chloroacetoacetonitrile; 2-Chloro-3-oxobutyronitrile; Acetoacetonitrile, 2-chloro-; Butyronitrile, 2-chloro-3-oxo-; α-Chloroacetoacetonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Oxo-Butyronitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.