Description

(S)-(-)-Ethyl Leucate CAS NO 60856-85-1 is a high-purity, single-enantiomer chiral building block and intermediate of significant importance in asymmetric synthesis. Its defined stereochemistry makes it a valuable precursor for the production of pharmaceuticals, agrochemicals, and fine chemicals where optical purity is critical. This compound is essential for research and development chemists and manufacturers in the pharmaceutical, biotechnology, and advanced material sectors seeking to introduce specific chiral centers into complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing drugs for metabolic and neurological disorders.
• Asymmetric Catalyst Ligand Precursor: Used in the preparation of chiral ligands for metal-catalyzed reactions, enabling high enantioselectivity in industrial chemical processes.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators with improved efficacy and environmental profiles.
• Fine Chemical and Flavor/Fragrance Production: Employed in the synthesis of complex, optically active aroma chemicals and specialty fine chemicals.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic routes to chiral compounds.
• Peptidomimetics and Bioactive Molecule Construction: Utilized as a constrained amino acid derivative in the design of peptide analogs and other bioactive compounds.

Basic Information

Product Name	(S)-(-)-Ethyl Leucate
CAS No.	60856-85-1
Molecular Formula	C8H16O3
Molecular Weight	160.21 g/mol
Synonyms	(S)-Ethyl 2-hydroxy-4-methylpentanoate; L-Ethyl leucate; (-)-Ethyl leucate; Ethyl (S)-(-)-2-hydroxy-4-methylvalerate; (S)-(-)-2-Hydroxy-4-methylpentanoic acid ethyl ester; Ethyl L-2-hydroxyisocaproate; (2S)-2-Hydroxy-4-methylpentanoic acid ethyl ester
EINECS	Contact for details

Quality Control

We maintain a stringent quality management system to ensure the chemical and chiral purity of our (S)-(-)-Ethyl Leucate meets the exacting standards of our global clientele. Every batch is characterized using advanced analytical techniques including chiral HPLC, NMR, and GC-MS to verify identity, purity, and enantiomeric excess (ee). A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]	-15° to -20° (c=1, EtOH)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.