Description

3,4-Difluorothiophenol is a high-value organosulfur and organofluorine building block essential for advanced chemical synthesis. This compound matters for its unique reactivity profile, where the thiol group and strategically placed fluorine atoms enable the construction of complex molecular architectures. It is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the difluorothiophenol moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Polymer and Material Science: Incorporated into monomers for producing high-performance polymers, liquid crystals, and electronic materials with specific optical or conductive properties.
• Chemical Research & Development: A versatile reagent for constructing sulfur-containing heterocycles and fluorinated aromatic compounds in academic and industrial research.

Basic Information

Product Name	3,4-Difluorothiophenol
CAS No.	60811-24-7
Molecular Formula	C6H4F2S
Molecular Weight	146.16 g/mol
Synonyms	3,4-Difluorobenzenethiol; 3,4-Difluorophenyl mercaptan; 1,2-Difluoro-4-mercaptobenzene; 3,4-Difluorothiophenol; 60811-24-7; 3,4-Difluorobenzenethiol; 4-Mercapto-1,2-difluorobenzene
EINECS	Contact for details

Quality Control

Our 3,4-Difluorothiophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Due to its sensitivity, allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.