Description

Cys-Tyr-Ile-Thr-Asn-Cys-Gly-Leu-Gly-Nh2 is a synthetic nonapeptide amide with a cyclic disulfide bridge, known in the industry as a key intermediate for research and development. This compound is valued for its structural role in studying peptide conformation, stability, and receptor interactions. It is primarily sought by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in peptide chemistry and drug discovery programs. The product is supplied to meet the stringent purity requirements of advanced scientific applications.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or reference standard in the synthesis and study of novel therapeutic peptides.
• Bioconjugation & Probe Development: Utilized for creating labeled peptides or peptide-drug conjugates due to its reactive cysteine residues.
• Structure-Activity Relationship (SAR) Studies: Employed to investigate the impact of specific amino acid sequences and disulfide bonds on biological activity and stability.
• Biochemical Assay Development: Used as a substrate or inhibitor in enzymatic assays to study protease activity or other protein-peptide interactions.
• Academic Research: Applied in university laboratories for teaching and fundamental research in peptide synthesis, folding, and analysis.
• Reference Standard: Provides a high-purity benchmark for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	Cys-Tyr-Ile-Thr-Asn-Cys-Gly-Leu-Gly-Nh2
CAS No.	60786-59-6
Molecular Formula	C41H64N12O13S2
Molecular Weight	973.15 g/mol
Synonyms	CYITNCLG-NH2 (Disulfide bridge); Cys-Tyr-Ile-Thr-Asn-Cys-Gly-Leu-Gly Amide; Cyclo(CYITNCLG); H-Cys-Tyr-Ile-Thr-Asn-Cys-Gly-Leu-Gly-NH2 (cyclic 1-6); Nonapeptide amide (CYITNCLG); [Cys1, Cys6]-CYITNCLG-NH2; Peptide CYITNCLG (cyclic)
EINECS	Contact for details

Quality Control

Our Cys-Tyr-Ile-Thr-Asn-Cys-Gly-Leu-Gly-Nh2 is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We adhere to a quality management system suitable for supplying research-grade materials to the global scientific community.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 70.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.