Description

5-Iodo-5,6-Dihydrouracil is a halogenated derivative of the uracil heterocycle, serving as a versatile synthetic intermediate in advanced organic chemistry. This compound is valued for its role in constructing modified nucleosides and nucleotides, which are critical for pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Agrochemical Research: Used in developing new classes of pesticides and herbicides with specific modes of action.
• Biochemical Probe: Serves as a modified base in oligonucleotide synthesis for studying nucleic acid structure and function.
• Academic & Contract Research: Essential reagent in university and CRO laboratories for methodological development in heterocyclic chemistry.
• Process Chemistry: Employed in scaling up synthetic routes for potential drug candidates during preclinical development.

Basic Information

Product Name	5-Iodo-5,6-Dihydrouracil
CAS No.	60763-80-6
Molecular Formula	C4H5IN2O2
Molecular Weight	240.00 g/mol
Synonyms	5-Iododihydrouracil; 5-Iodo-5,6-dihydro-2,4(1H,3H)-pyrimidinedione; 5-Iodo-5,6-dihydropyrimidine-2,4(1H,3H)-dione; 5-Iododihydro-2,4(1H,3H)-pyrimidinedione; 5-Iodo-5,6-dihydro-1H-pyrimidine-2,4-dione
EINECS	Contact for details

Quality Control

Our 5-Iodo-5,6-Dihydrouracil is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting your regulatory and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.