Description

Toxin I (Anemonia Sulcata) is a potent neurotoxin peptide isolated from the sea anemone *Anemonia sulcata*. This compound is of significant interest for its high-affinity interaction with voltage-gated sodium channels, making it a critical tool for neurological and pharmacological research. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic manufacturers for studying ion channel function, developing novel therapeutics, and creating biochemical assays.

Application

• Neuroscience Research: As a specific modulator of voltage-gated sodium channels (NaV channels) for electrophysiology studies and channel characterization.
• Pharmacology & Drug Discovery: A key tool compound for screening and developing new analgesic, antiarrhythmic, or anticonvulsant drug candidates targeting ion channels.
• Biochemical Assay Development: Used in the development of high-throughput screening (HTS) assays and diagnostic kits for channelopathy research.
• Toxicology Studies: Employed as a reference standard in marine toxin research and environmental safety assessments.
• Academic & Industrial R&D: Serves as a precise molecular probe for basic research in cellular signaling and membrane biophysics.

Basic Information

Product Name	Toxin I (Anemonia Sulcata)
CAS No.	60748-44-9
Molecular Formula	C164H256N50O49S7
Molecular Weight	~4,800 Da
Synonyms	ATX I; Anemonia sulcata Toxin I; Sea Anemone Toxin I; Sodium Channel Neurotoxin from Anemonia sulcata; ATXI; AsTX; Neurotoxin I (Anemonia sulcata); Anemone Toxin I
EINECS	Contact for details

Quality Control

Our Toxin I (Anemonia Sulcata) is produced and handled under strict quality protocols suitable for research applications. Each batch is characterized to ensure identity, purity, and biological activity. Certificates of Analysis (COA) detailing purity (by HPLC), peptide content, and activity are available upon request. We adhere to relevant quality management standards to ensure batch-to-batch consistency and reliability for your critical research.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Biological Activity	Confirmed by functional assay
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.