Description

4-Amino-5-(Benzyloxy)Pyrimidin-2(1H)-One is a high-purity pyrimidine derivative, a crucial advanced pharmaceutical intermediate (API intermediate) valued for its role in synthesizing complex bioactive molecules. Its structural features make it a key building block in modern medicinal chemistry, particularly for the development of antiviral and anticancer agents. This compound is essential for R&D laboratories and production facilities in the pharmaceutical and fine chemical sectors requiring reliable, high-quality intermediates for scale-up and process optimization.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of nucleoside analogs and other active pharmaceutical ingredients (APIs) with potential antiviral or anticancer activity.
• Biochemical Research: Used as a substrate or precursor in enzymatic studies and for probing biological pathways involving pyrimidine metabolism.
• Organic Synthesis: Serves as a versatile starting material for constructing complex heterocyclic compounds in academic and industrial research settings.
• Agrochemical Development: Potential intermediate in the research and synthesis of novel crop protection agents and herbicides.
• Material Science Research: Investigated as a precursor for specialty chemicals and functional materials due to its aromatic and heterocyclic structure.

Basic Information

Product Name	4-Amino-5-(Benzyloxy)Pyrimidin-2(1H)-One
CAS No.	60722-62-5
Molecular Formula	C11H11N3O2
Molecular Weight	217.23 g/mol
Synonyms	4-Amino-5-benzyloxypyrimidin-2(1H)-one; 2(1H)-Pyrimidinone, 4-amino-5-(phenylmethoxy)-; 5-(Benzyloxy)-4-aminopyrimidin-2(1H)-one; 4-Amino-5-(phenylmethoxy)-2(1H)-pyrimidinone; 4-Amino-5-benzyloxy-2-hydroxypyrimidine; 4-Amino-5-O-benzyl-2-pyrimidone
EINECS	Contact for details

Quality Control

Our production of 4-Amino-5-(Benzyloxy)Pyrimidin-2(1H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released according to comprehensive in-house specifications, which typically include identity confirmation (IR, NMR), purity assay (HPLC), and control of related substances. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.