Description

2,3-Dihydro-7-Nitro-2-Oxo-5-Phenyl-1H-1,4-Benzodiazepine-3-Carboxylic Acid is a key benzodiazepine derivative and a crucial synthetic intermediate in advanced organic chemistry. This compound matters for its role in the development and research of novel pharmaceutical agents, particularly within the central nervous system (CNS) therapeutic area. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the research and development of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for CNS-targeting drugs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Industrial R&D: Employed in synthetic organic chemistry research for exploring new heterocyclic compound libraries and reaction pathways.
• Precursor for Further Functionalization: The carboxylic acid moiety allows for derivatization into esters, amides, and other conjugates for expanded chemical exploration.

Basic Information

Product Name	2,3-Dihydro-7-Nitro-2-Oxo-5-Phenyl-1H-1,4-Benzodiazepine-3-Carboxylic Acid
CAS No.	60676-80-4
Molecular Formula	C16H11N3O5
Molecular Weight	325.28 g/mol
Synonyms	7-Nitro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepine-2-one-3-carboxylic acid; 3-Carboxy-7-nitro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 5-Phenyl-7-nitro-1,3-dihydro-2H-1,4-benzodiazepine-2-one-3-carboxylic acid; 7-Nitro-5-phenyl-3H-1,4-benzodiazepine-3-carboxylic acid, 1,2-dihydro-2-oxo-; 60676-80-4; 1H-1,4-Benzodiazepine-3-carboxylic acid, 2,3-dihydro-7-nitro-2-oxo-5-phenyl-
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-7-Nitro-2-Oxo-5-Phenyl-1H-1,4-Benzodiazepine-3-Carboxylic Acid is produced under strict quality management protocols. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.