Description

H-Met-Trp-Oh CAS NO 60535-02-6 is a high-purity dipeptide derivative, specifically the protected form of the methionine-tryptophan sequence. This compound serves as a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptides and proteins. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors developing novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: Key raw material for the synthesis of therapeutic peptides targeting metabolic disorders, neurological conditions, and oncology.
• Biochemical Research: Used as a protected amino acid sequence in academic and industrial research for studying protein structure, function, and peptide hormones.
• Peptide Library Synthesis: A fundamental component in the combinatorial chemistry production of peptide libraries for drug discovery and high-throughput screening.
• Cosmetic Peptides: Intermediate in the manufacture of bioactive peptides for advanced skincare formulations aimed at anti-aging and skin repair.
• Enzyme Substrate Analog: Employed in the development of specific substrates or inhibitors for proteolytic enzyme studies.

Basic Information

Item	Details
Product Name	H-Met-Trp-Oh
CAS No.	60535-02-6
Molecular Formula	C17H21N3O3S
Molecular Weight	347.43 g/mol
Synonyms	Methionyltryptophan; L-Methionyl-L-tryptophan; H-Met-Trp-OH; Methionine Tryptophan Dipeptide; N-(Methoxycarbonyl)-L-methionyl-L-tryptophan; Boiling Point: 605.2±55.0 °C; Mettryptophane; Fmoc-Met-Trp-OH (related protected form)
EINECS	Contact for details

Quality Control

Our H-Met-Trp-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, chiral analysis to confirm stereochemical integrity, and identity confirmation via spectroscopic methods. We provide Certificates of Analysis (COA) with detailed batch-specific data to ensure traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	-30.0° to -35.0° (c=1 in DMF)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Single Impurity (HPLC)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.