Description

n-(4-Fluorophenyl)Pyridin-2(1H)-One is a high-purity fluorinated heterocyclic compound, serving as a critical building block in advanced organic synthesis. Its unique structure makes it a valuable intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for its role in creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorophenyl moiety enhances biological activity and stability.
• Material Science Research: Serves as a precursor for organic electronic materials, including ligands for metal-organic frameworks (MOFs) and components for organic light-emitting diodes (OLEDs).
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and exploring novel fluorination chemistry.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	n-(4-Fluorophenyl)Pyridin-2(1H)-One
CAS No.	60532-42-5
Molecular Formula	C11H8FNO
Molecular Weight	189.19 g/mol
Synonyms	2(1H)-Pyridinone, 1-(4-fluorophenyl)-; 1-(4-Fluorophenyl)-2(1H)-pyridinone; 1-(4-Fluorophenyl)pyridin-2(1H)-one; N-(4-Fluorophenyl)-2-pyridone; 4-Fluoro-N-(2-oxo-1,2-dihydropyridin-1-yl)aniline; 60532-42-5; FC-1012 (Potential Research Code)
EINECS	Contact for details

Quality Control

Every batch of n-(4-Fluorophenyl)Pyridin-2(1H)-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the rigorous standards required for pharmaceutical and advanced chemical synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.