Description

(Deamino-Cys1,D-Orn8)-Vasopressin is a synthetic analogue of the endogenous hormone arginine vasopressin, specifically engineered to exhibit potent and selective V2 receptor agonist activity. This modification is critical for applications requiring enhanced antidiuretic effects with reduced pressor activity compared to the native peptide. It is an essential high-purity intermediate and active ingredient for advanced pharmaceutical research and development, particularly in endocrinology and nephrology. Target industries include pharmaceutical manufacturers, biotechnology research firms, and contract development organizations focused on metabolic and renal disorders.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of drugs targeting diabetes insipidus and related fluid balance disorders.
• Biomedical Research: Used as a selective V2 receptor agonist in preclinical studies to investigate renal physiology, water reabsorption mechanisms, and novel therapeutic pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Peptide Chemistry & Conjugation: A key building block for the synthesis of more complex peptide conjugates or drug delivery systems due to its defined biological activity.
• Diagnostic Development: Potential use in the development of diagnostic assays or kits for evaluating vasopressin receptor function and related disorders.

Basic Information

Product Name	(Deamino-Cys1,D-Orn8)-Vasopressin
CAS No.	60498-04-6
Molecular Formula	C46H65N13O12S2
Molecular Weight	1032.2 g/mol
Synonyms	Desmopressin Impurity C; DDAVP Impurity C; 1-Desamino-8-D-ornithine Vasopressin; [1-β-Mercaptopropionic acid, 8-D-ornithine] Vasopressin; Deamino-D-Arg8-Vasopressin (common misnomer); dAVP; D-Orn8-Vasopressin, 1-Deamino-; (1-β-Mercaptopropionic acid, 8-D-ornithine)-Vasopressin
EINECS	Contact for details

Quality Control

Our (Deamino-Cys1,D-Orn8)-Vasopressin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical research. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP guidelines where applicable for non-clinical and investigational use.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0% (on anhydrous basis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.