Description

H-Met-Arg-Oh CAS NO 60461-10-1 is a high-purity, synthetic tripeptide composed of L-histidine, L-methionine, and L-arginine. This compound serves as a critical building block and reference standard in advanced biochemical research and pharmaceutical development. It is essential for researchers and manufacturers in the fields of peptide synthesis, proteomics, and metabolic pathway studies, where precise molecular structure and purity are paramount for reliable results.

Application

• Pharmaceutical Research & Development: Used as a key intermediate in the synthesis of novel therapeutic peptides and peptidomimetics targeting various biological pathways.
• Biochemical Reference Standard: Serves as a high-purity calibrant and standard in analytical methods such as HPLC and mass spectrometry for peptide quantification and identification.
• Proteomics and Enzymology Studies: Employed as a substrate or inhibitor model to study enzyme kinetics, protease activity, and protein-protein interactions.
• Nutritional Science Research: Investigated for its potential role in metabolic studies due to its constituent amino acids, which are involved in methylation, nitric oxide synthesis, and histamine pathways.
• Cosmeceutical Ingredient Synthesis: Acts as a precursor in the development of bioactive peptides for advanced skincare formulations aimed at anti-aging and skin repair.

Basic Information

Product Name	H-Met-Arg-Oh
CAS No.	60461-10-1
Molecular Formula	C17H31N7O5S
Molecular Weight	445.54 g/mol
Synonyms	Histidylmethionylarginine; H-His-Met-Arg-OH; L-Histidyl-L-methionyl-L-arginine; Methionylhistidylarginine; Arg-Met-His; Tripeptide HMR; HMAR; CAS 60461-10-1
EINECS	Contact for details

Quality Control

Every batch of H-Met-Arg-Oh is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, MS, and NMR analyses to verify identity, purity, and conformity. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and easily oxidized nature. For long-term storage, desiccants are recommended. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 98.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.