Description

(2,4-Dioxo-1,2,3,4-Tetrahydro-Pyrimidin-5-Ylamino)-Fumaric Acid Dimethyl Ester is a specialized heterocyclic building block and pharmaceutical intermediate of significant commercial interest. This compound matters for its role as a key synthon in the synthesis of complex molecules, particularly in medicinal chemistry and advanced material science. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of uracil and pyrimidine derivatives with potential biological activity.
• Medicinal Chemistry Research: Used in the discovery and development of new drug candidates, particularly for antiviral, anticancer, and CNS-targeted therapies.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the multi-step synthesis of complex specialty chemicals and advanced organic compounds.
• Biochemical Research: Utilized as a modified nucleobase analog in biochemical studies and probe development.
• Material Science: Potential monomer or precursor for creating polymers with specific electronic or photonic properties.

Basic Information

Product Name	(2,4-Dioxo-1,2,3,4-Tetrahydro-Pyrimidin-5-Ylamino)-Fumaric Acid Dimethyl Ester
CAS No.	60458-95-9
Molecular Formula	C11H13N3O6
Molecular Weight	283.24 g/mol
Synonyms	5-[(2,4-Dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)amino]-2-butenedioic acid dimethyl ester; Dimethyl (2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-ylamino)fumarate; 5-Aminouracil fumaric acid dimethyl ester adduct; (5-Amino-2,4-dihydroxypyrimidin-6-yl)amino-fumaric acid dimethyl ester; N-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-butenediamidic acid dimethyl ester; 5-[(2,4-Dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)amino]fumaric acid dimethyl ester
EINECS	Contact for details

Quality Control

Our (2,4-Dioxo-1,2,3,4-Tetrahydro-Pyrimidin-5-Ylamino)-Fumaric Acid Dimethyl Ester is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and manufacturing applications. Certificates of Analysis (COA) detailing specifications and test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be kept under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.