Description

H-Aib-Obzl is a protected amino acid derivative, specifically the benzyl ester of 2-aminoisobutyric acid (Aib), a key non-proteinogenic amino acid. This compound is a crucial building block in peptide synthesis, offering enhanced stability and conformational control in the resulting peptide chains. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and bioactive compounds.

Application

• Peptide Synthesis Building Block: As a protected derivative for the solid-phase and solution-phase synthesis of complex peptides.
• Conformational Studies: Incorporation into peptide sequences to induce specific helical or folded structures due to the steric constraints of the Aib residue.
• Pharmaceutical Research: Intermediate in the research and development of peptide-based drugs, antimicrobial peptides, and hormone analogs.
• Peptidomimetic Design: Used to create stable analogs of natural peptides with improved metabolic stability and bioavailability.
• Biochemical Research: Tool compound for studying enzyme-substrate interactions and protein folding mechanisms.
• Material Science: Potential monomer for the synthesis of bio-inspired polymers and advanced biomaterials.

Basic Information

Product Name	H-Aib-Obzl
CAS No.	60421-20-7
Molecular Formula	C11H15NO2
Molecular Weight	193.24 g/mol
Synonyms	2-Aminoisobutyric Acid Benzyl Ester; Benzyl 2-Aminoisobutyrate; H-Aib-OBzl; Aib-OBzl; Boc-Aib-OBzl (when protected); (2-Methyl-2-aminopropanoic acid) benzyl ester; α-Aminoisobutyric acid benzyl ester; 2-Methylalanine benzyl ester
EINECS	Contact for details

Quality Control

Our H-Aib-Obzl is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical and pharmaceutical intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.