Description

H-Ala-Ala-Otbu Hcl is a protected dipeptide building block of significant importance in synthetic organic and medicinal chemistry. Its primary value lies in its role as a key intermediate for the controlled synthesis of more complex peptides and peptidomimetics. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly in the development of active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the solid-phase and solution-phase synthesis of peptide-based drugs and APIs.
• Biochemical Research: Used in academic and industrial R&D for studying peptide structure-activity relationships (SAR) and enzyme-substrate interactions.
• Protease Inhibitor Development: Serves as a core structure or precursor in the design and synthesis of protease inhibitors.
• Combinatorial Chemistry: Employed in the generation of diverse peptide libraries for high-throughput screening in drug discovery.
• Peptidomimetic Synthesis: Acts as a starting material for creating modified peptides with enhanced stability and bioavailability.
• Custom Peptide Service: A fundamental reagent for contract research organizations (CROs) and CDMOs offering custom peptide synthesis services.

Basic Information

Product Name	H-Ala-Ala-Otbu Hcl
CAS No.	60417-38-1
Molecular Formula	C₁₀H₂₁N₂O₃·HCl
Molecular Weight	252.75 g/mol
Synonyms	H-Ala-Ala-OtBu hydrochloride; L-Alanyl-L-alanine tert-butyl ester hydrochloride; N-(tert-Butoxycarbonyl)-L-alanyl-L-alanine; Boc-Ala-Ala-OtBu HCl; Ala-Ala-OtBu·HCl; tert-Butyl L-alanyl-L-alaninate hydrochloride; 2-[(2-Aminopropanoyl)amino]propanoic acid tert-butyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our H-Ala-Ala-Otbu Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and GMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.