Description

4-Phenyl-Pyrimidine-2-Thiol is a versatile heterocyclic building block featuring a pyrimidine core substituted with a phenyl group and a thiol moiety. This compound matters as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and material science. Industries that need it include pharmaceutical R&D for drug discovery, agrochemical development, and organic electronics for advanced materials.

Application

• Pharmaceutical intermediate for the synthesis of kinase inhibitors and other bioactive molecules.
• Building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• Precursor for ligands in catalysis and coordination chemistry.
• Key raw material in the research and development of agrochemicals.
• Intermediate in the synthesis of organic semiconductors and electronic materials.
• Starting material for the preparation of functionalized pyrimidine derivatives.

Basic Information

Product Name	4-Phenyl-Pyrimidine-2-Thiol
CAS No.	60414-59-7
Molecular Formula	C10H8N2S
Molecular Weight	188.25 g/mol
Synonyms	2-Mercapto-4-phenylpyrimidine; 4-Phenyl-2-pyrimidinethiol; 2-Pyrimidinethiol, 4-phenyl-; 4-Phenyl-2-mercaptopyrimidine; 2-Thiol-4-phenylpyrimidine; 4-Phenylpyrimidine-2-thione; 2(1H)-Pyrimidinethione, 4-phenyl-
EINECS	Contact for details

Quality Control

Our 4-Phenyl-Pyrimidine-2-Thiol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.