Description

n-Acetyl-Demethylmuramyl-Alanyl-Isoglutamine is a synthetic muramyl dipeptide (MDP) derivative, a key structural component of bacterial peptidoglycan. This compound is of significant interest for its role as a potent immunomodulator and adjuvant, capable of stimulating the innate immune system. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for vaccine development, immunological studies, and as a reference standard in analytical chemistry.

Application

• Immunological Research: As a model compound for studying NOD2 receptor activation and innate immune signaling pathways.
• Vaccine Adjuvant Development: Investigated for its potential to enhance the efficacy and longevity of immune responses in next-generation vaccine formulations.
• Pharmaceutical Intermediates: Serves as a critical synthetic intermediate or building block for more complex immunostimulatory compounds.
• Analytical Reference Standard: Used in HPLC, LC-MS, and NMR for method development, validation, and quality control of related biological products.
• Cell Culture & In Vitro Studies: Applied in research to modulate macrophage and dendritic cell activity in experimental models.

Basic Information

Product Name	n-Acetyl-Demethylmuramyl-Alanyl-Isoglutamine
CAS No.	60355-77-3
Molecular Formula	C19H32N4O10
Molecular Weight	476.48 g/mol
Synonyms	N-Acetylmuramyl-L-alanyl-D-isoglutamine; MDP (Muramyl Dipeptide); N-Acetylmuramyl-Alanyl-Isoglutamine; Ac-MDP; L-Ala-D-isoGln-MDP; Adjuvant Peptide; 6-O-2-Acetamido-2-deoxy-β-D-glucopyranosyl-(1→4)-N-acetylmuramyl-L-alanyl-D-isoglutamine
EINECS	Contact for details

Quality Control

Our n-Acetyl-Demethylmuramyl-Alanyl-Isoglutamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (NMR, IR), purity assessment by HPLC, and determination of residual solvents and moisture content. We provide full traceability and a Certificate of Analysis (COA) with every shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.