Description

(Des-Tyr1)-Leu-Enkephalin is a synthetic peptide analog of the endogenous opioid peptide Leu-Enkephalin. This compound is a critical research tool for studying opioid receptor pharmacology, specifically the delta (δ) opioid receptor subtype, due to its selective binding profile. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biochemical suppliers focused on neuroscience, pain management, and neuropharmacology. The product is supplied as a high-purity material to ensure reliable and reproducible experimental results.

Application

• Neuroscience Research: A key ligand for investigating the structure, function, and signaling pathways of delta opioid receptors in the central nervous system.
• Pharmacological Studies: Used in receptor binding assays and functional studies to screen and characterize novel analgesic compounds.
• Biochemical Standard: Serves as a reference standard in analytical methods such as HPLC and mass spectrometry for peptide quantification and identification.
• Drug Discovery: Employed in early-stage discovery programs targeting opioid receptors for the development of new pain therapeutics with potentially reduced side effects.
• Academic & Educational Use: Utilized in university laboratories for teaching advanced concepts in neurochemistry and peptide biology.

Basic Information

Product Name	(Des-Tyr1)-Leu-Enkephalin
CAS No.	60254-83-3
Molecular Formula	C₂₇H₃₅N₅O₇
Molecular Weight	529.60 g/mol
Synonyms	H-Gly-Gly-Phe-Leu-OH; Leu-Enkephalin, (Des-Tyr1)-; [Des-Tyrosine¹]-Leucine-enkephalin; Leu-Enkephalin (2-5); Gly-Gly-Phe-Leu; GGFL; Opioid peptide fragment (2-5); Delta opioid receptor ligand
EINECS	Contact for details

Quality Control

Every batch of (Des-Tyr1)-Leu-Enkephalin is manufactured and tested under strict quality management systems. We guarantee high purity levels suitable for demanding research applications, with comprehensive analytical testing including HPLC for purity and MS for identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.