Description

H-Ala-Phe-Nh2 Hcl is a high-purity dipeptide derivative, specifically the hydrochloride salt of the L-Alanyl-L-Phenylalanine amide. This compound serves as a crucial building block (protected amino acid) in solid-phase peptide synthesis (SPPS) and other advanced chemical syntheses. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and life science sectors for developing novel therapeutic peptides and biochemical tools.

Application

• Pharmaceutical Intermediate: A key raw material for the synthesis of complex peptide-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or precursor in enzymatic studies and metabolic pathway investigations.
• Peptide Library Construction: Essential for combinatorial chemistry and high-throughput screening to discover new drug candidates.
• Protecting Group Strategy: The amide and hydrochloride functionalities make it a valuable reagent in multi-step organic synthesis requiring specific protecting groups.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in peptide manufacturing.

Basic Information

Product Name	H-Ala-Phe-Nh2 Hcl
CAS No.	60240-16-6
Molecular Formula	C12H18N3O2·HCl
Molecular Weight	273.75 g/mol
Synonyms	L-Alanyl-L-phenylalanine amide hydrochloride; H-Ala-Phe-NH2·HCl; Ala-Phe-amide HCl; Alanylphenylalanine amide hydrochloride; 2-[(2-Amino-1-oxopropyl)amino]-3-phenylpropanoic acid amide hydrochloride; N-(2-Amino-1-oxopropyl)-L-phenylalaninamide hydrochloride; (S)-2-((S)-2-Aminopropanamido)-3-phenylpropanamide hydrochloride
EINECS	Contact for details

Quality Control

Our H-Ala-Phe-Nh2 Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.