Description

5-Chloro-3H-Quinazolin-4-One is a versatile and high-value heterocyclic organic compound that serves as a critical synthetic intermediate in advanced chemical manufacturing. Its unique quinazolinone core, functionalized with a reactive chlorine atom, makes it an essential building block for constructing complex molecular architectures. This compound is primarily sought after by research institutions and industrial R&D departments within the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, particularly those targeting kinase inhibition and possessing potential anticancer or anti-inflammatory activities.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides by serving as a core scaffold for bioactive molecules.
• Material Science: Building block for creating specialized organic ligands, dyes, and photoactive compounds used in electronic materials and sensors.
• Academic & Contract Research: Fundamental reagent in medicinal chemistry and organic synthesis research for exploring new heterocyclic chemistry and structure-activity relationships (SAR).
• Chemical Library Synthesis: Employed in combinatorial chemistry and high-throughput screening to generate diverse compound libraries for biological evaluation.

Basic Information

Product Name	5-Chloro-3H-Quinazolin-4-One
CAS No.	60233-66-1
Molecular Formula	C8H5ClN2O
Molecular Weight	180.59 g/mol
Synonyms	5-Chloroquinazolin-4(3H)-one; 5-Chloro-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 5-chloro-; 5-Chloro-4-hydroxyquinazoline; 5-Chloro-3,4-dihydro-4-oxoquinazoline; 5-Chloro-4-quinazolinol; 5-Chloro-4-quinazolinone
EINECS	Contact for details

Quality Control

Our 5-Chloro-3H-Quinazolin-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) that include results from HPLC, NMR, and mass spectrometry. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.