Description

Protein C is a crucial vitamin K-dependent glycoprotein that functions as a key natural anticoagulant in the blood plasma. Its primary value lies in its ability to inactivate specific clotting factors, thereby regulating the coagulation cascade and preventing excessive blood clot formation. This product is essential for research and development in the life sciences, pharmaceutical manufacturing, and diagnostic industries, particularly for studies related to hemostasis, thrombosis, and the development of therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical active pharmaceutical ingredient (API) or starting material in the production of anticoagulant and antithrombotic therapies.
• Biochemical Research: Used as a standard or reagent in laboratory studies to investigate blood coagulation pathways, protein-protein interactions, and enzymatic activity.
• Diagnostic Reagent Manufacturing: A key component in the formulation of diagnostic kits and assays for measuring Protein C activity or antigen levels in clinical samples to diagnose deficiencies.
• Cell Culture & Biotechnology: Employed in specialized cell culture media and bioprocessing applications where the modulation of coagulation is required.
• Reference Standard: Utilized as a high-purity calibrant or control material in quality control laboratories for ensuring the accuracy of diagnostic and clinical tests.

Basic Information

Product Name	Protein C
CAS No.	60202-16-6
Molecular Formula	C45H69N11O10S2 (Representative for active site peptide)
Molecular Weight	Approx. 62,000 Da (Glycoprotein)
Synonyms	Autoprothrombin IIA; Blood Coagulation Factor XIV; Coagulation Factor XIV; Anticoagulant Protein C; Activated Protein C (APC); Vitamin K-Dependent Protein C; PROC; Plasma Protein C
EINECS	Contact for details

Quality Control

Our Protein C is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including purity assay, activity determination, and impurity profiling, to ensure it meets rigorous standards for research and industrial use. Certificates of Analysis (COA) detailing specific results for parameters such as biological activity, purity by HPLC, and endotoxin levels are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. Due to its sensitivity, the product should be handled under controlled conditions to prevent oxidation and degradation. Keep container sealed under an inert atmosphere when possible.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (SDS-PAGE / HPLC)	≥ 95%
Biological Activity	≥ 150 IU/mg
Endotoxin	< 1.0 EU/mg
Moisture Content (KF)	< 5.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.