Description

4-Bromo-2,6-dimethoxypyrimidine is a versatile brominated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its value lies in its dual functionality, where the bromine atom serves as an excellent leaving group for cross-coupling reactions, and the methoxy groups can be further modified. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially nucleoside analogs and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection chemicals.
• Material Science Research: Serves as a monomer or building block for creating functional polymers and advanced organic materials.
• Cross-Coupling Reactions: Employed in Suzuki, Stille, and Buchwald-Hartwig amination reactions to introduce the pyrimidine scaffold into larger molecular architectures.
• Chemical Biology: Used as a probe or tag in medicinal chemistry for structure-activity relationship (SAR) studies.
• Laboratory Reagent: Acts as a standardized reagent for method development and scale-up processes in process chemistry.

Basic Information

Product Name	4-Bromo-2,6-dimethoxypyrimidine
CAS No.	60186-89-2
Molecular Formula	C6H7BrN2O2
Molecular Weight	219.04 g/mol
Synonyms	4-Bromo-2,6-dimethoxypyrimidine; 2,6-Dimethoxy-4-bromopyrimidine; 4-Bromo-2,6-bis(methoxy)pyrimidine; Pyrimidine, 4-bromo-2,6-dimethoxy-; 4-Brom-2,6-dimethoxypyrimidin; 60186-89-2; 4-Br-2,6-(OMe)2Py
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,6-dimethoxypyrimidine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.