Description

4(3H)-Quinazolinone, 3-Amino-2-(4-Chlorophenyl)-6,8-Bis(Phenylmethoxy)- is a high-purity, multi-functional quinazolinone derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and versatile synthetic intermediate for developing novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in creating new therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Chemical Biology Probes: Serves as a core structure for developing enzyme inhibitors or receptor modulators for biological pathway studies.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value heterocyclic compounds for specialty applications.
• Agrochemical Research: Investigated as a precursor for novel active ingredients in crop protection products.

Basic Information

Product Name	4(3H)-Quinazolinone, 3-Amino-2-(4-Chlorophenyl)-6,8-Bis(Phenylmethoxy)-
CAS No.	60186-45-0
Molecular Formula	C28H22ClN3O3
Molecular Weight	483.95 g/mol
Synonyms	3-Amino-2-(4-chlorophenyl)-6,8-bis(benzyloxy)quinazolin-4(3H)-one; 3-Amino-2-(p-chlorophenyl)-6,8-dibenzyloxy-4(3H)-quinazolinone; 6,8-Dibenzyloxy-3-amino-2-(4-chlorophenyl)-4(3H)-quinazolinone; 2-(4-Chlorophenyl)-3-amino-6,8-bis(phenylmethoxy)-4(3H)-quinazolinone; Quinazolinone derivative 60186-45-0; 3-Amino-2-(4-chlorophenyl)-6,8-bis(benzyloxy)quinazolinone
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.