Description

Met-Enkephalinamide is a synthetic peptide analog of the endogenous opioid peptide Met-Enkephalin, modified at the C-terminus to enhance its stability and biological activity. This compound is a critical research tool for studying opioid receptor pharmacology, pain pathways, and neurobiological signaling. It is primarily utilized by pharmaceutical R&D teams, academic neuroscientists, and biochemical researchers focused on developing novel analgesic compounds and understanding neuropeptide function.

Application

• Neuroscience Research: Used as a selective ligand in receptor binding assays and functional studies of delta (δ) and mu (μ) opioid receptors.
• Analgesic Drug Development: Serves as a reference standard and lead compound in the discovery of new, non-addictive pain management therapies.
• Biochemical Assays: Employed in enzyme inhibition studies and to investigate the metabolism of enkephalins by peptidases.
• Cell Signaling Studies: Applied in vitro to study the effects of opioid receptor activation on intracellular second messenger systems (e.g., cAMP inhibition).
• Pharmaceutical Reference Standard: Used for quality control and analytical method development in peptide-based pharmaceutical manufacturing.

Basic Information

Product Name	Met-Enkephalinamide
CAS No.	60117-17-1
Molecular Formula	C27H35N5O7S
Molecular Weight	573.66 g/mol
Synonyms	Methionine Enkephalinamide; Tyr-Gly-Gly-Phe-Met-NH2; [Met5]-Enkephalinamide; H-Tyr-Gly-Gly-Phe-Met-NH2; Opioid Peptide (Met-Enkephalin, Amide); YGGFM-NH2; Met-Enkephalin amide; L-Tyrosylglycylglycyl-L-phenylalanyl-L-methioninamide
EINECS	Contact for details

Quality Control

Our Met-Enkephalinamide is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for peptide synthesis and can provide material traceable to primary reference standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Assay (HPLC)	≥ 97% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.