Description

2-Amino-1,7-Dihydro-6H-Purin-6-One Monohydrobromide is a high-purity, pharmaceutically relevant purine derivative, specifically the hydrobromide salt form of a key heterocyclic building block. This compound is valued for its role as a critical synthetic intermediate in the development of nucleoside analogs and other bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, antiviral drug discovery, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of nucleoside analogs and purine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in the discovery and development of new therapeutic agents targeting viral infections and other diseases.
• Biochemical Research: Serves as a precursor or standard in studies involving purine metabolism and related enzymatic pathways.
• Antiviral Drug Development: Particularly relevant for the synthesis of compounds with potential activity against a range of viruses.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for use in multi-step GMP or non-GMP production campaigns.
• Reference Standard: Can be qualified for use as an analytical reference standard in quality control laboratories.

Basic Information

Product Name	2-Amino-1,7-Dihydro-6H-Purin-6-One Monohydrobromide
CAS No.	60049-89-0
Molecular Formula	C5H6BrN5O
Molecular Weight	232.04 g/mol
Synonyms	2-Aminohypoxanthine Hydrobromide; 2-Amino-6-hydroxypurine Hydrobromide; 6-Hydroxy-2-aminopurine Hydrobromide; 2-Amino-1H-purin-6(7H)-one Hydrobromide; 2-Amino-6-oxo-1,6-dihydropurine Hydrobromide; 2-Amino-6-purinol Hydrobromide; Guanine isomer Hydrobromide
EINECS	Contact for details

Quality Control

Our 2-Amino-1,7-Dihydro-6H-Purin-6-One Monohydrobromide is manufactured under controlled conditions to ensure high chemical purity and lot-to-lot consistency, suitable for demanding research and development applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥97% by HPLC), and impurity profiles. We adhere to stringent internal quality standards and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.