Description

4,6-Dichloro-5-Acetylpyrimidine is a versatile and high-value halogenated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring reactive chlorine atoms and an acetyl group, makes it an indispensable intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other potential therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry and material science for structure-activity relationship (SAR) studies.
• API Development: Employed in the development and scale-up of Active Pharmaceutical Ingredients (APIs) requiring functionalized pyrimidine cores.
• Dye & Pigment Intermediate: Can be utilized in the synthesis of specialized heterocyclic dyes and functional materials.

Basic Information

Product Name	4,6-Dichloro-5-Acetylpyrimidine
CAS No.	60025-06-1
Molecular Formula	C6H4Cl2N2O
Molecular Weight	191.02 g/mol
Synonyms	5-Acetyl-4,6-dichloropyrimidine; 4,6-Dichloro-5-pyrimidinyl methyl ketone; 2,4-Dichloro-5-acetylpyrimidine; 5-Acetyl-2,4-dichloropyrimidine; 1-(4,6-Dichloropyrimidin-5-yl)ethanone; NSC 403697
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-5-Acetylpyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements of our clients in research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.